Machines+People is not yet registered with Apple as an approved application. As such it will need to be configured to run on any machine that supports that feature. It will run on 10.6 machines.

There doesn’t seem to be any issue with Windows machines.

On Linux machines the application will not run from the USB drive for privileges reasons. This will get addressed. Until that happens you will have to copy it to the machine you want to run it on. Leave the database on the USB drive. After running you can delete the application or leave it.